[Skip to Navigation]
Views 338
Citations 0
Ophthalmic Images
August 13, 2020

Choroidal Deposits in a Patient With Mucopolysaccharidoses Type 1

Author Affiliations
  • 1Department of Ophthalmology, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, Pennsylvania
JAMA Ophthalmol. 2020;138(8):e194435. doi:10.1001/jamaophthalmol.2019.4435

A 6-year-old girl with mucopolysaccharidoses type 1 with a Hurler-Scheie phenotype, who was receiving weekly enzyme replacement therapy, presented for an ophthalmological evaluation. Her best-corrected visual acuity was 20/50 OD and 20/40 OS. Mild corneal clouding was noted. Fundus photography and spectral-domain optical coherence tomography showed choroidal deposits in both eyes (Figure). Comprehensive visual electrophysiology testing had normal results. There was no progression over the next 3 years.

Limit 200 characters
Limit 25 characters
Conflicts of Interest Disclosure

Identify all potential conflicts of interest that might be relevant to your comment.

Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.

Err on the side of full disclosure.

If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.

Not all submitted comments are published. Please see our commenting policy for details.

Limit 140 characters
Limit 3600 characters or approximately 600 words
    ×