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JAMA Ophthalmology Clinical Challenge
August 20, 2020

An African American Man With Progressive Loss of Iris Pigmentation in Both Eyes

Author Affiliations
  • 1Illinois Eye and Ear Infirmary, University of Illinois at Chicago, Chicago
JAMA Ophthalmol. 2020;138(10):1089-1090. doi:10.1001/jamaophthalmol.2020.1417

A 37-year-old African American man in good health presented to the Illinois Eye and Ear Infirmary in Chicago. The patient noted 4 years of progressive, decreased, patchy pigmentation of both eyes; constant photophobia; and constant decreased visual acuity. He had a history of high myopia and a family history of glaucoma in a female family member. He denied other prior ocular history, trauma, or eye surgery. A review of systems had no remarkable findings, and the patient denied a prodromal viral illness.

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