[Skip to Navigation]
Views 788
Citations 0
JAMA Ophthalmology Clinical Challenge
September 3, 2020

Presumed Sickle Cell Retinopathy in an Elderly Woman

Author Affiliations
  • 1The Retina Service of Wills Eye Hospital, Mid Atlantic Retina, Philadelphia, Pennsylvania
JAMA Ophthalmol. 2020;138(11):1205-1206. doi:10.1001/jamaophthalmol.2020.1614

A 60-year-old African American woman presented with a 1-day history of new floaters in her right eye. She had no relevant medical history, was not taking any systemic or ocular medications, and denied a history of floaters. Her visual acuity was 20/40 OU, and her intraocular pressure was 18 mm Hg OU. An anterior segment examination was unremarkable in both eyes. Ophthalmoscopy findings were notable for a vitreous hemorrhage in the right eye. Salmon-patch intraretinal hemorrhages were noted in the temporal peripheral retina of both eyes (Figure 1). Widefield fluorescein angiography revealed retinal capillary nonperfusion of the peripheral retina with neovascularization elsewhere, in a sea fan–like pattern, in both eyes. The patient denied any known history of sickle cell disease or trait and any family history of sickle disease. Scatter laser photocoagulation was performed on the nonperfused temporal retina in the right eye, and the left eye was observed.

Add or change institution
Limit 200 characters
Limit 25 characters
Conflicts of Interest Disclosure

Identify all potential conflicts of interest that might be relevant to your comment.

Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.

Err on the side of full disclosure.

If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.

Not all submitted comments are published. Please see our commenting policy for details.

Limit 140 characters
Limit 3600 characters or approximately 600 words