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Invited Commentary
October 29, 2020

Of Age-Related Macular Degeneration and Vitamins

Author Affiliations
  • 1Kresge Eye Institute (emeritus), Wayne State University School of Medicine, Detroit, Michigan
JAMA Ophthalmol. 2020;138(12):1290. doi:10.1001/jamaophthalmol.2020.4417
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    1 Comment for this article
    D3 level
    H Silverstein, MD | Preventive Mediicine Center
    Simply because the Institute of Medicine thinks 800 to 1,000 IU is the correct dose vitaminD3 does not make 2,000 IU D3 "supraphysiologic." In fact to achieve the the blood levels (25 OH D3 50-66 nanograms/mL) of less technologically developed societies that are more sun-exposed and likely closer to standard physiologic requirements, 5,000 IU D3 a day is required. Meant with respect and simply clarification. HRS