A patient with a history of varicella-zoster virus infection presented with a complaint of photoaversion in the right eye. On examination, the pupil in the right eye was fixed and nonreactive to light. Slitlamp examination revealed transillumination defects in the right iris. A dilated fundus examination revealed multiple depigmented abnormalities in the right choroid (Figure). The left eye was unremarkable. Optical coherence tomography revealed no overlying retinal pigment epithelium atrophy in areas of depigmentation, which was likely secondary to loss of pigmentation of choroidal melanocytes.
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Long CP, Bakhoum MF, Freeman WR. Depigmented Chorioretinal Lesions Following Varicella-Zoster Virus Infection. JAMA Ophthalmol. 2020;138(11):e201652. doi:10.1001/jamaophthalmol.2020.1652
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