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JAMA Ophthalmology Clinical Challenge
November 19, 2020

Persistent Red Eye Unresponsive to Topical Treatment

Author Affiliations
  • 1Tennent Institute of Ophthalmology, Gartnavel General Hospital, Glasgow, United Kingdom
  • 2Institute of Neurological Sciences, Department of Neuroradiology, Queen Elizabeth University Hospital, Glasgow, United Kingdom
JAMA Ophthalmol. Published online November 19, 2020. doi:10.1001/jamaophthalmol.2020.4062

A 68-year-old woman presented to the emergency eye clinic with a 3-week history of progressive left eye redness and discomfort unresponsive to topical antibiotics or lubricants, as prescribed by her optometrist. The intraocular pressure (IOP) was raised (26 mm Hg) and was treated with a topical β-blocker. Otherwise, her condition was managed conservatively for presumed viral conjunctivitis.

She self-presented 6 days later with intermittent visual blurring, mild eyelid swelling, and conjunctival chemosis. The IOP remained raised (24 mm Hg). An inflammatory or allergic etiology was suspected; therefore, topical corticosteroids and a prostaglandin analogue were also prescribed.

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