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Invited Commentary
November 25, 2020

Zika Virus and Anterior Uveitis—4 Years After the Pandemic

Author Affiliations
  • 1National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore
  • 2Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore
  • 3Singapore Eye Research Institute, Singapore
  • 4Department of Ophthalmology, National University Hospital, Singapore
  • 5National Centre for Infectious Diseases, Singapore
JAMA Ophthalmol. 2021;139(1):103-104. doi:10.1001/jamaophthalmol.2020.5138

It has been more than 4 years since the World Health Organization declared the Zika virus (ZIKV) outbreak of 2016 a Public Health Emergency of International Concern. Although the worst of the pandemic may be over, today there are still sporadic outbreaks in both Southeast Asia and South Asia. The origins of the 2016 pandemic was purported to be a new American subclade emerging from the Asian lineage of the RNA flavivirus. This story serves as a chilling reminder that these sporadic outbreaks should not be underestimated, given their potential to result in another pandemic.

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