It has been more than 4 years since the World Health Organization declared the Zika virus (ZIKV) outbreak of 2016 a Public Health Emergency of International Concern. Although the worst of the pandemic may be over, today there are still sporadic outbreaks in both Southeast Asia and South Asia. The origins of the 2016 pandemic was purported to be a new American subclade emerging from the Asian lineage of the RNA flavivirus. This story serves as a chilling reminder that these sporadic outbreaks should not be underestimated, given their potential to result in another pandemic.