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Invited Commentary
December 10, 2020

In-depth Understanding and Prevention of Cataract Surgery–Related Descemet Membrane Detachment

Author Affiliations
  • 1Moorfields Eye Hospital and University College London Institute of Ophthalmology, London, England
JAMA Ophthalmol. 2021;139(2):155-156. doi:10.1001/jamaophthalmol.2020.5395

Descemet membrane detachment (DMD) is one of the most commonly seen complications associated with cataract surgery. Although DMD resolves spontaneously in a considerable proportion of cases, it is a potentially vision-threatening condition owing to the possibility of causing persistent corneal edema and corneal endothelial decompensation.1 Various factors have been reported to be associated with cataract surgery–related DMD, such as sharpness of the surgical instruments, location and size of the incision, patient’s age, coexisting corneal pathologies, predisposition related to mutation of the transforming growth factor β–induced gene, and surgical time.1-3

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