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JAMA Ophthalmology Clinical Challenge
December 23, 2020

A Man With a Cloudy Cornea

Author Affiliations
  • 1Department of Ophthalmology and Visual Sciences, Vanderbilt Eye Institute, Nashville, Tennessee
  • 2Department of Pathology, Vanderbilt University Medical Center, Nashville, Tennessee
JAMA Ophthalmol. Published online December 23, 2020. doi:10.1001/jamaophthalmol.2020.4646

A 77-year-old man was referred to the cornea service for painless, progressive blurring of vision in his left eye. His best-corrected visual acuity was 20/40 OS, and the patient reported that his vision had waxed and waned over several months. His ocular history included cataract surgery in the left eye, followed by yttrium-aluminum-garnet capsulotomy 2 months before his referral. Of note, he had recently undergone Mohs surgery and subsequent reconstruction for squamous cell carcinoma in situ of the lateral canthus in the fellow eye; he also had a medical history of multiple skin malignant neoplasms.

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