The express industry provides door-to-door deliveries of goods (eg, DHL or FedEx) or services (eg, visiting nurse care or mobile nail salons). These industries have made life potentially easier and more convenient, in that people can get goods or services without leaving home. Their use also has expanded throughout the world, even in areas where such services previously were not popular.1 As coronavirus disease 2019 (COVID-19) has catalyzed the incorporation of telemedicine into ophthalmic care,2 the field seems ready to expand into home monitoring of ophthalmic diseases, such as the neovascular form of age-related macular degeneration (nAMD) or diabetic macular edema. Managing these conditions may involve millions of office monitoring visits. However, if research shows that some monitoring of visual acuity and structural changes in the macula can be done from the home to determine when office visits are needed for evaluation or treatment, without sacrificing visual acuity outcomes, or to even provide treatment, such as an intravitreous injection in the home by a qualified health care professional, then such monitoring may transform current ophthalmic care not only during a pandemic but thereafter, especially if accompanied by reduced costs, improved utilization of services, and greater patient satisfaction. The approach also might have applications in assisted living or nursing home environments.