A 58-year-old woman with interstitial cystitis presented for pentosan polysulfate (Elmiron) maculopathy screening. She reported no visual symptoms or ocular history, and routine eye examination results 6 months prior were reportedly normal. She was diagnosed with interstitial cystitis in 2004 and had been taking pentosan polysulfate, 100 mg twice daily, for 4½ years for a cumulative dose of 324 g. Her medical history was otherwise significant for moderate bilateral hearing loss detected in early childhood and type 2 diabetes, hyperlipidemia, and hypothyroidism treated with a therapeutic regimen of metformin, pravastatin, and levothyroxine supplementation, respectively.
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Meyer BI, Jain N. Salt-and-Pepper Retinopathy in a Woman With Hearing Loss. JAMA Ophthalmol. 2021;139(6):668–669. doi:10.1001/jamaophthalmol.2020.4624
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