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JAMA Ophthalmology Clinical Challenge
May 20, 2021

Iris Mass in a 14-Month-Old Boy

Author Affiliations
  • 1Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, Florida
  • 2Retina Consultants, PC, Hartford, Connecticut
  • 3Sylvester Comprehensive Cancer Center, University of Miami School of Medicine, Miami, Florida
JAMA Ophthalmol. 2021;139(7):802-803. doi:10.1001/jamaophthalmol.2020.5301

A 14-month-old boy presented with a sudden-onset, rapidly enlarging lesion in the right eye detected by his parents 2 weeks earlier. The patient had normal tracking bilaterally. Under anesthesia, findings from an examination of the right eye revealed an inferonasal translucent gray-white iris mass with numerous intralesional lacy cystic structures (Figure 1). There was no microphthalmia, cataract, lens subluxation, anterior or posterior synechiae, glaucoma, or uveitis. Findings from a fundus examination were normal. High-resolution anterior segment echography results revealed an iridociliary mass that extended posteriorly to the pars plicata with overall dimensions of 7.7 × 6.0 × 1.9 mm. There were no associated calcifications, retrolental membranes, or seeding.

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