Patching and Atropine for Severe Amblyopia: Are Both Better Than Patching Alone?

Guidance on the treatment of amblyopia has benefited substantially from outcomes obtained from randomized clinical trials (RCTs). Most RCTs on amblyopia treatment have been conducted by the National Eye Institute–supported Pediatric Eye Disease Investigator Group (PEDIG). The PEDIG public website¹ shows the breadth of amblyopia research reported by that group and provides a key resource not only for guiding amblyopia eye care professionals, but also for instructing the design, conduct, and interpretation of contemporary clinical research on amblyopia treatment.