Stickler syndrome is a congenital disorder that affects the production of collagen.1 The most important sign is the presence of congenital abnormalities of the vitreous body. The vitreous body is generally hypoplastic and may have a “beaded” appearance. These composite images acquired using ultra-widefield retinal imaging show the hypoplastic vitreous in a 9-year-old patient with a presumed ocular-only variant of Stickler syndrome. To our knowledge, this is the first image that shows the entire vitreous hypoplasia of a patient with this condition. Peripheral degenerations (Figure, white arrowheads) are also typical findings in these patients. Children diagnosed with Stickler syndrome should be monitored regularly because of the high risk of retinal detachment.2
Ortiz-Salvador M, Montero-Hernández J, Freiría-Barreiro R. Hypoplasic Vitreous in Stickler Syndrome. JAMA Ophthalmol. 2021;139(9):e213312. doi:10.1001/jamaophthalmol.2021.3312
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