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JAMA Ophthalmology Clinical Challenge
March 17, 2022

Unilateral Yellowish Eye in a Woman With an Intraocular Mass

Author Affiliations
  • 1Ocular Oncology Service, Department of Ophthalmology and Visual Sciences, Princess Margaret Cancer Centre/University Health Network, University of Toronto, Toronto, Ontario, Canada
JAMA Ophthalmol. 2022;140(5):540-541. doi:10.1001/jamaophthalmol.2021.5683

A 65-year-old woman was referred with a 6-week history of blurry vision, ocular pain, and subconjunctival yellow discoloration in the left eye. Suspicious retinal detachment and intraocular mass were identified, which raised concerns for choroidal melanoma. No symptoms or signs were reported in the right eye. Her ocular history included bilateral cataract surgery 5 years prior. Review of systems yielded negative results, including for ocular trauma, jaundice, and cutaneous melanoma. She had no history of tobacco use.

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