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June 1999

Innovation and Clinical Trials

Arch Ophthalmol. 1999;117(6):846. doi:

The editorial by Bressler1 entitled "Evaluating New Retinal Imaging Techniques" stimulated us to consider the question of when it is appropriate to call for prospective and/or randomized clinical trials methodology early on in the development of diagnostic or therapeutic techniques. Our recent article2 prompted the editorial by Dr Bressler.