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April 2000

Primary Orbital Ewing Sarcoma in a Middle-aged Woman

Arch Ophthalmol. 2000;118(4):592. doi:

We read with great interest the Clinicopathologic Report by Choi et al1 that reported a case of orbital Ewing sarcoma in a 43-year-old woman. The authors believed that their case was the first reported of orbital Ewing sarcoma in an adult beyond the fourth decade of life.

We previously performed a literature review on 8 other cases of orbital Ewing sarcoma.2 To our knowledge, the second reported case of orbital Ewing sarcoma in the literature was in a 61-year-old man described by Yamada and Takahashi3 in 1957. The patient had gradual visual loss and proptosis of the right eye. The right eye was enucleated, and radiation therapy was performed, which resulted in regression of the tumor. Two months after radiotherapy, the tumor recurred, and the patient subsequently died. Findings from autopsy showed a tumor in the right orbit with extension into the cranial fossa.3