NEW ENGLAND JOURNAL OF MEDICINE
Hemangiomas in Children
Beth A. Drolet, MD; Nancy B. Esterly, MD; Ilona J. Frieden, MD
Hemangiomas are the most common soft-tissue tumors of infancy, occurring in approximately 5 to 10 percent of one-year-old children. Despite the frequency of these tumors, their pathogenesis is not completely understood, and the best approach to their management remains controversial. Research on angiogenesis, an improved knowledge of the classification of the vascular anomalies of infancy, advances in imaging techniques, recently identified complications, and new therapeutic approaches, such as treatment with interferon and lasers, have altered our understanding of this common childhood problem and the way we approach it.
N Engl J Med. 1999;341:173-181.Reprints: Beth A. Drolet, MD, Pediatric Dermatology, Medical College of Wisconsin, Froedert East, 9200 W Wisconsin Ave, Milwaukee, WI 53226 (e-mail: email@example.com).
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