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From the Archives of the Archives
July 2000

A look at the past . . .

Arch Ophthalmol. 2000;118(7):917. doi:10-1001/pubs.Ophthalmol.-ISSN-0003-9950-118-7-eya0140

Some pathologists believe that sarcoidosis is a type of noncaseating tuberculosis, while others maintain that it is a separate disease entity of unknown origin. The similarity of the clinical manifestations of sarcoidosis and tuberculosis and the resemblance of the biopsy findings frequently make the differential diagnosis of these diseases difficult. In cases in which the presence of acid-fast bacilli can be demonstrated, there is no question about the diagnosis; in the absence of clinical signs of tuberculosis and in cases in which examination fails to disclose Mycobacterium tuberculosis, the biopsy findings may be considered characteristic of either tuberculosis or sarcoidosis.

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