A HEALTHY 28-year-old Pakistani woman developed fever, malaise, and diffuse edema, rapidly progressing to multiple organ failure with encephalopathy, anuric renal failure, hemolytic anemia, and thrombocytopenia. The patient was diagnosed with thrombotic thrombocytopenic purpura (TTP) and treated with hemodialysis, intravenous corticosteroids, and plasma exchange with cryoprecipitate-poor plasma. After 2 weeks, her mental status improved, but she complained of bilateral vision loss.
Schwartz SG, McPherson AR, Mieler WF, Sessoms SL, Moake JL, Holz ER. Bilateral Combined Occlusion of the Central Retinal Artery and Vein Secondary to Thrombotic Thrombocytopenic Purpura. Arch Ophthalmol. 2000;118(9):1304–1305. doi:10.1001/archopht.118.9.1304
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