Lubbers reports on eleven cases of multiple sclerosis. In nine there were ophthalmoscopic changes in the disc (atrophy and neuritis). In seven there was a central scotoma and normal peripheric field; in one a scotoma with contraction of the field; in two irregular peripheric contraction; and in one case the field was normal. In seven cases ocular muscles were affected. All the patients had nystagmus.
Reference:Arch Ophththalmol. 1898;27:143.
A look at the past . . . Arch Ophthalmol. 2000;118(9):1250. doi:10.1001/archopht.118.9.1250
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