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November 2003

Botulinum Toxin and Human Serum Albumin

Arch Ophthalmol. 2003;121(11):1661. doi:10.1001/archopht.121.11.1661-a

Botox (Allergan Inc, Irvine, Calif) and Dysport (Ipsen Ltd, Slough, Berkshire, England) are the 2 commercially available botulinum toxin type A products; both contain human serum albumin (HSA) to stabilize the neurotoxin complex and prevent it from aggregating on surfaces.1,2 Human serum albumin is also found in Myobloc (Elan Pharmaceuticals Inc, San Diego, Calif), a new botulinum toxin type B product, registered for use in the United States and Europe but not in Australia.3