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November 2004

Diffuse Intraocular Dispersion of Triamcinolone Particles as a Causeof Sterile Endophthalmitis

Author Affiliations

Copyright 2004 American Medical Association. All Rights Reserved.Applicable FARS/DFARS Restrictions Apply to Government Use.2004

Arch Ophthalmol. 2004;122(11):1733. doi:10.1001/archopht.122.11.1733-a

We read with interest the article by Roth et al1 describingthe occurrence of 7 cases of noninfectious endophthalmitis associated withintravitreal triamcinolone injection. They hypothesize that the clinical signsof endophthalmitis that they observed, namely anterior chamber cells and flare,posterior segment vitritis, and hypopyon, probably represented a toxic inflammatoryreaction to the drug or the vehicle in which it was suspended.