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April 2006

Ocular Brucellosis vs Vogt-Koyanagi-Harada Syndrome

Arch Ophthalmol. 2006;124(4):608-609. doi:10.1001/archopht.124.4.608

We read with interest the article entitled “Bilateral Multifocal Choroiditis With Serous Retinal Detachment in a Patient With Brucella Infection: Case Report and Review of the Literature” by Rabinowitz et al1 in the January 2005 issue of the ARCHIVES. Rabinowitz and colleagues described a 39-year-old man of Arab-Bedouin origin with bilateral disc hyperemia and exudative retinal detachments. A history of ingestion of unpasteurized milk prompted Brucella serologic testing, which was positive at a titer of 1:160 but with negative cultures. They concluded that the patient had Brucella uveitis. They treated him with streptomycin sulfate and doxycycline hyclate, with worsening of ocular signs and symptoms. Oral prednisone resulted in resolution of the detachments and improvement in vision.

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