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September 2006

The Case for Observational Management of Suspected Small Choroidal Melanoma

Author Affiliations

NEIL M.BRESSLERMDAuthor Affiliations: Ocular Oncology Service, Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, Fla (Dr Murray); and Massachusetts Eye and Ear Infirmary, Boston (Dr Sobrin).

Arch Ophthalmol. 2006;124(9):1342-1344. doi:10.1001/archopht.124.9.1342

In December 1997, the ARCHIVES reported the outcome of the Collaborative Ocular Melanoma Study small tumor observational study documenting factors predictive of growth and treatment in this multicenter clinical trial.1 Accompanying that issue was an editorial that delineated the pros and cons to observation vs early treatment for small choroidal melanoma.2 In that editorial, an argument was made for a randomized clinical trial to definitively address the critical clinical question, “Do I treat now or do I wait?” Now approaching the latter half of a decade from this discussion, we as the ophthalmologists managing patients with suspected small choroidal melanomas are still faced with the dilemma as to the best treatment approach for these patients.

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