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November 2006

Effects of Intravitreous Injection of Preserved and Nonpreserved Triamcinolone in Rabbit Retina

Arch Ophthalmol. 2006;124(11):1666. doi:10.1001/archopht.124.11.1666-a

We read with interest the article by Dierks et al1comparing the short-term effects of intravitreal injection of Kenalog-40 (Bristol-Myers Squibb, Princeton, NJ) with intravitreal injection of the vehicle and of triamcinolone acetonide in rabbit eyes. A 10% to 25% increase in a- and b-wave electroretinographic amplitudes of eyes with intravitreal injection of Kenalog-40 or triamcinolone compared with noninjected eyes was reported, although the probability of this being a chance finding (P value) was not stated.

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