A 1-year-old girl was initially seen in December 2003 (Figure 1 and Figure 2). Examination under anesthesia confirmed Axenfeld-Rieger syndrome. Follow-up in September 2004 showed new-onset corectopia in the right eye from an iridocorneal adhesion (Figure 3 and Figure 4). No corneal endothelial abnormalities, signs of uveitis, or systemic manifestations of Axenfeld-Rieger syndrome were present. Mild intraocular pressure elevation has been managed with latanoprost. No mutations in the PITX2 or FOXC1 genes were found. No further progression has occurred.
Honkanen R, Alward WL, Cossari AJ. Progressive Iris Changes in a Case of Axenfeld-Rieger Syndrome. Arch Ophthalmol. 2006;124(12):1793. doi:10.1001/archopht.124.12.1793
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