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Photo Essay
December 2006

Progressive Iris Changes in a Case of Axenfeld-Rieger Syndrome

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Copyright 2006 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2006

Arch Ophthalmol. 2006;124(12):1793. doi:10.1001/archopht.124.12.1793

A 1-year-old girl was initially seen in December 2003 (Figure 1 and Figure 2). Examination under anesthesia confirmed Axenfeld-Rieger syndrome. Follow-up in September 2004 showed new-onset corectopia in the right eye from an iridocorneal adhesion (Figure 3 and Figure 4). No corneal endothelial abnormalities, signs of uveitis, or systemic manifestations of Axenfeld-Rieger syndrome were present. Mild intraocular pressure elevation has been managed with latanoprost. No mutations in the PITX2 or FOXC1 genes were found. No further progression has occurred.

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