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November 2007

Effects of Desferoxamine on Retinal and Visual Function

Arch Ophthalmol. 2007;125(11):1581-1582. doi:10.1001/archopht.125.11.1581

We describe recovery of vision and postreceptor retinal function but not photoreceptor function following severe, acute visual impairment associated with high-dose desferoxamine (DFO) used to chelate iron in a 36-year-old woman with β-thalassemia major.1,2 Survival of patients with β-thalassemia necessitates long-term transfusion with consequent iron overload of vital organs, for which chelation therapy is mandatory.

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