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February 1, 2008

Misclassification: Who Really Lives in This Neighborhood?

Arch Ophthalmol. 2008;126(2):265-266. doi:10.1001/archophthalmol.2007.73

My ophthalmologic career might well have ended before it truly began. In an editorial prepared as a second-year resident, I decried the sorry state of clinical research (citing the shortcomings of published articles by leading academics) and called for the rigorous application of epidemiologic and statistical principles.1 Fortunately, those cited withheld retribution and, more often than not, graciously encouraged my efforts.

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