Nuel describes 16 cases of sympathetic amblyopia. In all except one, in which there had been a burn, a perforating injury had taken place, after which, often years later, amblyopia developed with partial atrophy of the nerve. The disturbance came on at a time when the injured eye was free from irritation, and even after an early enucleation had been done. The latter was of no avail when once the affection had appeared. The ophthalmoscopic picture consists in a woolliness of the disc and capillary hyperemia. Finally there is temporal atrophy; pure atrophy was never observed. The prognosis, as compared with other sympathetic affections, is favorable. Treatment with gray ointment and rest is of value, but the effect of enucleation of the injured eye is doubtful. The origin of the affection is doubtful.