That Archives is devoting this issue to genomics in ophthalmology just over 1 year from its 2 issues on genetics in ophthalmology is a testament to the fact that the era of genomic medicine is rapidly being incorporated into ophthalmology.1 The evolution of genetic medicine has been accelerated following the full sequencing of the human genome,2 the HapMap Project,3 and the identification of important genetic components to complex diseases, such as macular degeneration and glaucoma.4-7 Science has moved forward at a rapid pace. Now is the time to put this knowledge into clinical practice. Approximately 71% of respondents to a recent survey8 wanted more information from their physicians about genetic conditions in their families. Our patients are looking to us as ophthalmologists to take the lead.