The incurability of glaucoma seems to be due to the fact that ocular changes are consecutive and originate from an extra-ocular source, either the optic nerve or the afferent blood vessels. I cannot abandon my belief, stated in my first notes on glaucoma, that arterial atheroma is a factor. The whole question of glaucoma therapy took on a different aspect, however, when I realized that the blindness was to be attributed not to changes in the optic nerve, but to an increase in intra-ocular pressure. The choroiditis either subsides spontaneously or is controlled by the usual therapeutic measures, especially by antiphlogistics. The increased pressure, however, is the main cause of the damage, particularly of the excavation of the optic nerve. As a curative measure I propose that by some means or other a lowering of intra-ocular pressure be effected.
All efforts to produce a rapid outflow of fluid from
VON GRAEFE A. IRIDECTOMY IN GLAUCOMA: A STUDY OF THE GLAUCOMATOUS PROCESS. JAMA Ophthalmol. 1929;1(1):71–86. doi:10.1001/archopht.1929.00810010074004
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