Reports of cases of epibulbar squamous cell carcinoma or epithelioma are numerous, but cases in which the tumor is primary on the cornea are sufficiently rare to warrant reporting in each instance.
There is such a confusion of terms used in the literature for this pathologic condition that it is difficult to obtain a complete bibliography. Parsons.1 in 1904, could find only six cases reported in which the accuracy of the diagnosis of primary epithelioma of the cornea was probable. "The American Encyclopedia of Ophthalmology"2 quotes some of these and adds nine more cases, eight being reported under epithelioma and one under carcinoma.
A review of all cases of epibulbar carcinoma involving the cornea reported since then has shown only six cases3 in which primary involvement of the cornea could not be doubted. This brings the total number of cases reported to twenty-one. To this I
JUDD JH. PRIMARY SQUAMOUS CELL CARCINOMA OF THE CORNEA: REPORT OF A CASE. Arch Ophthalmol. 1929;2(2):133–137. doi:10.1001/archopht.1929.00810020140002
Artificial Intelligence Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.