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December 1929


Arch Ophthalmol. 1929;2(6):692-698. doi:10.1001/archopht.1929.00810020715009

A considerable number of persons are blind because they have dense scar tissue over the surface of the cornea, the result, usually, of injuries or infected ulcers. In eyes otherwise normal, useful vision can be secured if this scar can be removed and replaced by transparent corneal tissue.

The work described in this thesis was undertaken in order to study the regeneration of the cornea after excision of part of it, in the hope of learning something of the factors that determine whether newly formed corneal tissue shall be clear or opaque. For reports of previous work on this problem, and for a bibliography, the reader is referred especially to Wiener,1 von Hippel,2 Salzer3 and Wolfrum and Boehmig.4

In this study the experimental material consisted of the eyes of fifty rabbits. Three series of experiments were undertaken. Ether anesthesia was used. Only one eye of eachanimal

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