Pathologic changes in the retina have always been of interest to the ophthalmologist because of their effect on vision, and to the internist because of their significance in the diagnosis and prognosis of systemic diseases. Sclerosis of the retinal vessels affects vision in the main only when it becomes sufficiently advanced to interfere with the nutrition of the retina or when it is complicated by hemorrhage or edema. Recognition of its early stages is of considerable value, however, in the study of diseases of the cardiovascular system, especially if its relationship to sclerosis in other parts of the body can be clearly defined. Much has been written both on the ophthalmoscopic signs of retinal arteriosclerosis and on its interpretative significance. In the latter especially, a distinct trend toward clarification of the situation can be noted during recent years. It has seemed interesting and valuable to review briefly
WAGENER HP. SCLEROSIS OF THE RETINAL ARTERIOLES. Arch Ophthalmol. 1930;3(3):335–345. doi:10.1001/archopht.1930.00810050087009
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