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May 1930


Arch Ophthalmol. 1930;3(5):599-621. doi:10.1001/archopht.1930.00810070105007

Krukenberg, in 1899, was the first to report this unusual type of pigmentation of the cornea. He described the lesion as brown, spindleshaped and symmetrical and occupying the deepest layers of the cornea. The line of pigment ran in a vertical direction, and he referred to it as "bilateral congenital melanosis of the cornea."

He described three cases, in all of which myopia was found, ranging from —1 to —9 diopters. The patients were all women over 45 years of age. Each had brown irides. Krukenberg expressed his belief that this condition occurred only in brown eyes. The size of the pigmented spindles varied from 4 by 3 mm. to 3 by 4.5 mm. No adhesions or precipitates were seen, and the pigmentation of the cornea and irides was of the same color. Two of his patients had floating vitreous opacities and one had a bilateral posterior staphyloma.

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