[Skip to Navigation]
August 1930


Author Affiliations

From the Wilmer Institute, Johns Hopkins Hospital.

Arch Ophthalmol. 1930;4(2):174-179. doi:10.1001/archopht.1930.00810100020002

Coloboma of the lens is a congenital defect in the border of the lens together with a loss of lens substance, the lens otherwise being normal in shape. Although the condition is rare, the reported types are of considerable diversity, and several attempts at classification have been made. The edge of the defect may be straight, indented, curved in or projecting out. The majority of reported cases show the coloboma to be in the typical direction, downward, or down and slightly in or out. It also has been found upward, inward, up and in, up and out, and outward. Other congenital anomalies, such as coloboma of the iris, ciliary body and choroid, are frequently found associated with it. Coloboma lentis must be differentiated from ectopia lentis, in which the displaced lens often gives the impression of a defect. In ectopia, however, the margin of the lens shows no actual defect

Add or change institution