The case presented is reported for three reasons: (1) because of the relative infrequency of seeing optic atrophy in Paget's disease, (2) because of the unusual ocular symptoms presented and (3) because the bony changes involved primarily the sphenoidal region and caused a partial obliteration of the optic foramina and to a lesser extent of the sphenoidal fissures.
The literature reveals few reports by ophthalmologists of complications of the optic nerve in Paget's disease. Sir James Paget1 first described this disease before the Medico Chirurgical Society in 1876, and gave a complete picture which has not been improved on. Lawford R. Knaggs, in February, 1925, in the Hunterian Lecture before the Royal College of Surgeons in England, said that Paget's disease is "A very chronic disease of an inflammatory nature occurring in middle age or elderly people in which the normal osseous structure of the skeleton is removed,
AEBLI R. OPTIC ATROPHY IN PAGET'S DISEASE. Arch Ophthalmol. 1930;4(5):691–694. doi:10.1001/archopht.1930.00810130081007
Customize your JAMA Network experience by selecting one or more topics from the list below.