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November 1930

Anatomical Investigation of the Corticofugal Paths in Monkey and Rabbit

Arch Ophthalmol. 1930;4(5):793-796. doi:10.1001/archopht.1930.00810130183018

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During his systematic investigations of corticopetal optical conduction in Java monkeys in 1927, B. Brouwer questioned where the optical stimulations remain after reaching the area striata. In a series of monkeys and rabbits occipital and other cortical lesions were made and the secondary degenerations were studied in serial sections made by the Marchi method. Without doubt, important corticofugal connections were demonstrated with the corpus quadrigeminum as well as with the corpus geniculatum externum. Biemond systematically correlated this material for his doctorate thesis.

Ten Java monkeys' (Cynomolgus fascicularis) and four rabbits' brains were examined by the Marchi technic from sixteen to eighteen days after operation. The part of the brain that contained the corpus geniculatum externum, radiatio optica and area striata of the operated side was examined with controls from the crossed hemisphere. The frontal lobe, brain stem, medulla oblongata and spinal cord were also examined. Fibers were again found

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