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February 1931


Author Affiliations

From the Wilmer Ophthalmological Institute and the Department of Pathology of the Johns Hopkins Medical School.

Arch Ophthalmol. 1931;5(2):175-188. doi:10.1001/archopht.1931.00820020025002

A study of the eyes in thirty-two cases of septicemia obtained at autopsy has revealed a number of lesions not hitherto described in this condition. The cases of septicemia, as will be noted, were due to a variety of organisms. As a rule, only the posterior segment of the eyeballs was obtained for histologic examination. In this series no metastatic intra-ocular abscesses were found. Septic retinitis (Roth) was occasionally noted, but this subject has been dealt with so frequently that we have excluded our observations on this condition from our present report.


Marchesani,1 in his interesting investigations on the pathogenesis of sympathetic ophthalmia, reported the following experiment. Pure cultures of avirulent organisms (Staphylococcus albus and Bacillus xerosis) were injected repeatedly, at intervals of two weeks, into the vitreous of one eye of a rabbit. In a number of instances it was possible to demonstrate an