The discovery during the past years of an increasing number of pathologic conditions that may involve the optic nerves and chiasm and give rise to the clinical manifestations of optic atrophy, visual disturbances and perimetric field defects has constituted one of the most important advances in knowledge of the pathology, diagnosis and treatment of lesions about the optic chiasm. Following the reports of Marie and Fröhlich concerning the association of pituitary tumor with the clinical pictures of acromegaly and dystrophia adiposogenitalis, respectively, the attention of clinicians and surgeons was focused on these tumors, and in their diagnosis certain signs and symptoms were more or less insisted on. These included "sellar" headaches, subjective visual disturbances, primary optic atrophy, bitemporal hemianopia, an expanded sella turcica, with or without destruction of the clinoid processes, and metabolic disturbances indicated by acromegaly or Fröhlich's disease. It was appreciated that certain other signs
HEUER GJ, VAIL DT. CHRONIC CISTERNAL ARACHNOIDITIS PRODUCING SYMPTOMS OF INVOLVEMENT OF THE OPTIC NERVES AND CHIASM: PATHOLOGY AND RESULTS OF OPERATIVE TREATMENT IN FOUR CASES. Arch Ophthalmol. 1931;5(3):334–349. doi:10.1001/archopht.1931.00820030018002
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