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April 1931


Author Affiliations


Arch Ophthalmol. 1931;5(4):581-590. doi:10.1001/archopht.1931.00820040077005

Blastomycosis is a subacute or chronic disease due to a yeast fungus which attacks the skin and various internal organs, producing granulomatous and suppurative lesions and, particularly, small, chronic abscesses.

The first case was reported by Gilchrist1 in 1894 at a meeting of the American Dermatological Association. He had found an unusual disease of the skin in which peculiar bodies, with the appearance of parasites, were found. They were classified as balstomycetes. Six months later, Busse and Buschke2 reported a case of pyemia, that is, a systemic disease, caused by a pathogenic yeast of similar appearance. Then followed a considerable number of individual case reports by virious writer, including Stokes, Wells, Hessler, Hyde, Hektoen and Bevan,3 climaxed by the comprehensive article of Ricketts4 in 1901 in which he reviewed the cases on record and reported twelve new ones. In 1907, Hektoen5 and in 1908, Montgomery and