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May 1931


Arch Ophthalmol. 1931;5(5):754-759. doi:10.1001/archopht.1931.00820050076006

Before it was learned that the calcium metabolism of patients with senile cataract was within normal limits, and that they did not need treatment with parathyroid extract, it was thought that possibly they might benefit from the use of the latter. There had come to my attention certain unpublished reports on the use of various parathyroid extracts with more or less success. As calcium enters into the mechanism of so many physiologic processes, Collip thought it possible that clinical research would later indicate that it was desirable under definite circumstances to keep certain patients in a state of mild hypercalcemia. Besides, there were other possibilities: 1. Although the greater percentage of patients with cataract had more than sufficient calcium in their blood serum, the amount that was diffusing into the aqueous was insufficient to keep up a proper balance. 2. There was an excess of calcium in the

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