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October 1931


Arch Ophthalmol. 1931;6(4):578-581. doi:10.1001/archopht.1931.00820070602009

The pathologic changes that I shall describe were found in a buphthalmic eyeball, which was sent to me by the late Dr. Sprague, of Barre, Vt., with the following notes :

William B., aged 14 years. Right eye always blind. Whiteness of the pupil, as well as some enlargement of the globe, noticed by the nurse and by the mother at birth. Eye painful at night for the past three months. Globe markedly buphthalmic and tender to the touch. Lids closed with difficulty. Conjunctival and episcleral congestion. Cornea clear; iris bombé. Pupil, normal in size and fixed (no response to mydriatics), occupied by dense organized exudate. No fundus reflection. V. = no p. 1.; T.= N. Left eye, normal ; V.= 6/6 with a + 0.25 sphere.

The patient was the sixth of a family of nine children, none of whom was similarly affected. Syphilis could be excluded.

The globe was received at the

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