In connection with other investigations being carried on at the present time in hypertension, an attempt has been made to demonstrate a measurable change in the caliber of the retinal arteries before and during the administration of amyl nitrite, and to study by actual measurement the relation between the caliber of an artery and that of its associated vein in various degrees of hypertension.
The patients studied were selected entirely on the basis of blood pressure readings from a group of persons who were in sufficiently good health to be carrying on their usual work. Arbitrarily, a systolic level of 140 mm. was set as the upper limit of normal blood pressure, and at the time of the study of the eyegrounds, the blood pressure of the patients so selected was often found to be normal. These patients were, nevertheless, included in this study as a control group. In the
HAESSLER FH, SQUIER TL. MEASUREMENTS OF RETINAL VESSELS IN EARLY HYPERTENSION. Arch Ophthalmol. 1932;7(2):280–284. doi:10.1001/archopht.1932.00820090120009
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