Extensive injury to the eye has been particularly observed when skin lesions of the eyelids were too freely treated with radium, especially at a time when the danger to the eye from this treatment was not recognized. The ocular changes in the case to be described occurred in this way.
A woman, aged 31, was first seen in October, 1915, on account of a central choroiditis in the right eye which reduced her vision to fingers at 3 feet. The left eye, which was normal, presented an area of skin eruption at the outer canthus, of twelve years' standing, which had resisted all forms of treatment. In 1920, this area was treated with radium by an expert, which resulted in its healing. In the following year the left eye began to show some irritation, and in the course of the next years various changes occurred in the eye. In 1922,
Knapp A. A SERIES OF RADIUM INJURIES TO AN EYE. Arch Ophthalmol. 1932;7(4):619–620. doi:10.1001/archopht.1932.00820110133012
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