There are but few reports in the literature of localized calcareous degeneration of the sclera. The earliest of these was referred to by Pagenstecher1 as having appeared in the Blasii obs. med. ra Amstel. of 1677, concerning a case of circumscribed "ossification" of the sclera, which he believes to have been only a calcification, since osteoid transformation of the connective tissue does not seem to develop in the sclera.
In 1860, Pagenstecher1 himself reported a case of isolated calcification of the sclera, anterior to the insertion of a lateral rectus, in an atrophic eye. After extraction of the lime salts, the scleral fibers in the affected region were of normal appearance.
Katz2 was the first to point out the possibility of a primary localized necrosis of the sclera and a secondary deposition of calcium salts, as in his case the scleral fibers, after extraction of
KLIEN-MONCREIFF B. ISOLATED FOCI OF CALCIFICATION IN THE SCLERA: ANATOMIC AND CLINICAL ASPECTS. Arch Ophthalmol. 1932;7(5):757–762. doi:10.1001/archopht.1932.00820120109007
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