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Article
November 1932

TRANSPORTATION OF PARTICULATE MATTER FROM THE VITREOUS INTO THE OPTIC NERVE

Author Affiliations

NEW YORK
From the Department of Anatomy, Cornell University Medical College.

Arch Ophthalmol. 1932;8(5):695-710. doi:10.1001/archopht.1932.00820180067007
Abstract

The use of silver carbonate as a stain for the retina has shown that the internal limiting membrane of this organ appears as a close meshwork of fibers (Berliner1), probably formed by branches of MÜller's fibers and retinal astrocytes.

To ascertain whether or not this membrane would allow the passage of particulate matter into the retina we injected india ink into the posterior portion of the vitreous. The injections were made as soon as the needle was seen ophthalmoscopically to have perforated the retina, in such a way that the injected material tended to spread over the surface of the retina.

It was found that injected particles did not cross the internal limiting membrane, but that they were promptly removed by active phagocytic cells coming from the optic nerve and entering the vitreous.

Rabbits were used for the experiments. Some were albinos and others were

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