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I had just completed sectioning the cornea in the right eye of Dr. X., aged 56, a syphilitic patient with morphinomania, preliminary to doing an iridectomy for acute inflammatory glaucoma, when, to my great astonishment, the pupil made a series of quick changes, first becoming a long, narrow slit, then pyriform and then bulbous. After a few more minor contractions, all movements ceased, and the pupil again resumed its normal shape and contour ; I was then able to complete the operation without further delay. The color of a senile cataract present in the eye rendered these movements plain. There were no interruptions in the contractions as one shape merged imperceptibly into the other. It would be difficult to imagine anything more beautiful or graceful as the pupil, like a serpent, moved about. I knew that there was no other pathologic condition about the eye that could account for these deformations,